Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ic50 data for polymerid = 50000871,50003915,5269
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50506040(CHEMBL4536502)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H] 3-MC from AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50:  21nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50240990(2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  25nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of aryl hydrocarbon receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50269353(CHEMBL4105559)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50525572(CH-223191 | CHEMBL1743245)
Affinity DataIC50:  2.43E+3nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of FICZ-induced AhR transcriptional activity incubated for 24 hrs by Quanti-Lu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50:  5.20E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191436((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50:  5.40E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50269354(CHEMBL1335197)
Affinity DataIC50:  7.60E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50:  1.30E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191395((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrro...)
Affinity DataIC50:  1.88E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191405((2'Z,3'E)-7-bromoindirubin-3'-oxime | CHEMBL373834)
Affinity DataIC50:  2.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191422((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50:  2.40E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191396((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50:  2.50E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191415((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50191411((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: >3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed