Compile Data Set for Download or QSAR
maximum 50k data
Found 94 of ic50 data for polymerid = 50003963,50007219
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  5nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532885(CHEMBL4470017)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532885(CHEMBL4470017)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of mouse DAGLbeta expressed in HEK293T cell membranes using SAG as substrate preincubated for 30 mins followed by substrate addition by en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of mouse DAGLbeta expressed in HEK293T cell membranes using SAG as substrate preincubated for 30 mins followed by substrate addition by en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211260(CHEMBL3964338)
Affinity DataIC50:  13nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50:  25nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50:  25nMAssay Description:Inhibition of human GST-tagged DAGLbeta catalytic domain expressed in HEK293F cell membranes using EnzChek as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  40nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50:  40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50:  40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  40nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  40nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50240877(CHEMBL158897 | Quinolyl derivatives | cyclohexanon...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant DAGLbeta overexpressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50:  63nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50:  63nMAssay Description:Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211235(CHEMBL3974512)
Affinity DataIC50:  79nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant mouse DAGLbeta expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50:  79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532883(CHEMBL2136920)
Affinity DataIC50:  79nMAssay Description:Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50148187(CHEMBL3764093)
Affinity DataIC50:  80nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50:  100nMAssay Description:Inhibition of full length 3' FLAG-tagged mouse DAGLbeta expressed in African green monkey COS7 cells using sn-1-stearoyl-[14C]-arachidonoyl-glycerol ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50532882(CHEMBL4476210)
Affinity DataIC50:  100nMAssay Description:Inhibition of full length 3' FLAG-tagged mouse DAGLbeta expressed in African green monkey COS7 cells using sn-1-stearoyl-[14C]-arachidonoyl-glycerol ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50:  112nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50147617(CHEMBL3765421)
Affinity DataIC50:  146nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434899((2-benzylpiperidin-1-yl)(4-(4- (3,5-dichloropyridi...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434930(N-neopentyl-N-phenethyl-4-(4- (trifluoromethoxy)ph...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434935(N-neopentyl-N-(2-(pyridin-4- yl)ethyl)-4-(4- (trif...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434880((2-Benzylpiperidin-1-yl)(4-(4-(3,5-dimethoxypyridi...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434908((2-benzylpiperidin-1-yl)(4-(4- (4,6-dimethoxypyrim...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434933(N-(cyclopropylmethyl)-N- phenethyl-4-(4- (trifluor...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434882(N-(2-Ethylbutyl)-N-(2-(pyridin-4-yl)ethyl)-4-(4-(t...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434929(N-(2-ethylbutyl)-N-phenethyl-4- (4-(trifluorometho...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434928(N-cyclopropyl-N-phenethyl-4- (4-(trifluoromethoxy)...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434927(N-cyclobutyl-N-phenethyl-4-(4- (trifluoromethoxy)p...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434926(N-neopentyl-N-phenethyl-4-(4- (trifluoromethoxy)ph...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434925(N-(2-ethylbutyl)-N-phenethyl-4- (4-(trifluorometho...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434881((2-Benzylpiperidin-1-yl)(4-(2′,4′,6...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434920((2-benzylpiperidin-1-yl)(4-(6- bromopyridin-3-yl)-...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434919((2-benzylpiperidin-1-yl)(4-(4- nitrophenyl)-1H-1,2...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434892((4-([1,1'-biphenyl]-4-yl)-1H- 1,2,3-triazol-1-yl)(...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434918(4-(1-(2-benzylpiperidine-1- carbonyl)-1H-1,2,3-tri...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol lipase-beta(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM434913((2-benzylpiperidin-1-yl)(4-(4- methoxyphenyl)-1H-1...)
Affinity DataIC50: <400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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