Compile Data Set for Download or QSAR
maximum 50k data
Found 15 of ic50 data for polymerid = 50004020
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245464(CHEBI:52646 | LEPTOMYCIN B)
Affinity DataIC50:  1nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245476(CHEMBL4088268)
Affinity DataIC50:  10nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245473(CHEMBL4077955)
Affinity DataIC50:  25nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245464(CHEBI:52646 | LEPTOMYCIN B)
Affinity DataIC50:  151nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50527779(CHEMBL4440028)
Affinity DataIC50:  151nMAssay Description:Inhibition of CRM1 in human HCT-15 cells assessed as reduction in cell viability incubated for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50527777(CHEMBL4458289)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of nuclear CRM1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50240512(7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50540955(CHEMBL1450050)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50320332(8-(3-methylbut-2-enyl)-2H-chromen-2-one | CHEMBL10...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50303499(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50320333(7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one ...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50540956(CHEMBL4637077)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50540954(CHEMBL4645904)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50317384(CHEMBL1096042 | ethyl 5-(4-nitrophenyl)-4,6-dioxo-...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed