Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 data for polymerid = 50004553
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523902(2-amino-N-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  6.31nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523902(2-amino-N-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  6.46nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523865(2-amino-5-methyl-N-[1-(5-methyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  8.32nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523862(2-amino-5-fluoro-N-[1-(5-methyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  11nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523901(2-amino-5-chloro-N-[1-(5-methyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  15.8nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523862(2-amino-5-fluoro-N-[1-(5-methyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  19.5nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  90.8nMAssay Description:Inhibition of human MEKK6 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551987(CHEMBL4763562)
Affinity DataIC50:  201nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50552003(CHEMBL4764071)
Affinity DataIC50:  264nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  475nMAssay Description:Inhibition of human MEKK6 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50334268(CHEMBL1642655 | CHEMBL2205637 | N-(6-(1H-imidazol-...)
Affinity DataIC50:  510nMAssay Description:Inhibition of ASK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551995(CHEMBL4759182)
Affinity DataIC50:  742nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551972(CHEMBL4776637)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551992(CHEMBL4751918)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551988(CHEMBL4749551)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551989(CHEMBL4795965)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551977(CHEMBL4744931)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50552004(CHEMBL4753203)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551994(CHEMBL4750857)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551993(CHEMBL4778358)
Affinity DataIC50:  4.86E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50551998(CHEMBL4740051)
Affinity DataIC50:  4.99E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50552007(CHEMBL4796925)
Affinity DataIC50:  5.29E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50212258(GS-4997 | Selonsertib)
Affinity DataIC50:  6.25E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50552006(CHEMBL4752034)
Affinity DataIC50:  7.17E+3nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM50552005(CHEMBL4761865)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ASK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed