Compile Data Set for Download or QSAR
maximum 50k data
Found 48 of ic50 data for polymerid = 5618
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50015639(CHEMBL3260567 | USRE47141, Example 2)
Affinity DataIC50:  12nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564611(CHEMBL4788502)
Affinity DataIC50:  28nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564593(CHEMBL4777871)
Affinity DataIC50:  29nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564609(CHEMBL4791815)
Affinity DataIC50:  43nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50252542(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50:  44nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382318(CHEMBL2024685)
Affinity DataIC50:  44nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564612(CHEMBL4786439)
Affinity DataIC50:  45nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382325(CHEMBL2024693)
Affinity DataIC50:  46nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382324(CHEMBL2024691)
Affinity DataIC50:  47nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM282825(6-(4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of TGFbetaR1 in TGFbeta-stimulated mouse NIH3T3 cells assessed as reduction in SMAD3 phosphorylationMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564614(CHEMBL4797329)
Affinity DataIC50:  57nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)
Affinity DataIC50:  61nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382323(CHEMBL2024690)
Affinity DataIC50:  73nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  77nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564620(Ly-3200882 | Ly3200882 | US11691981, Compound A)
Affinity DataIC50:  83nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564603(CHEMBL4777294 | US11691981, Compound 77)
Affinity DataIC50:  87nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564610(CHEMBL4778362)
Affinity DataIC50:  90nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564598(CHEMBL4784194)
Affinity DataIC50:  92nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50015640(GALUNISERTIB | LY-2157299)
Affinity DataIC50: >100nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564608(CHEMBL4782867)
Affinity DataIC50:  102nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564613(CHEMBL4791582)
Affinity DataIC50:  103nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564617(CHEMBL4781326)
Affinity DataIC50:  116nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564605(CHEMBL4795823)
Affinity DataIC50:  116nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)
Affinity DataIC50:  117nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564594(CHEMBL4792452)
Affinity DataIC50:  119nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564615(CHEMBL4780548)
Affinity DataIC50:  127nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564616(CHEMBL4791955)
Affinity DataIC50:  134nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382319(CHEMBL2024686)
Affinity DataIC50:  135nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564604(CHEMBL4797447)
Affinity DataIC50:  136nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564595(CHEMBL4790322)
Affinity DataIC50:  162nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564601(CHEMBL4781586)
Affinity DataIC50:  188nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)
Affinity DataIC50:  211nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564599(CHEMBL4788673)
Affinity DataIC50:  225nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  236nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)
Affinity DataIC50:  274nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564618(CHEMBL4784622)
Affinity DataIC50:  283nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564602(CHEMBL4777610)
Affinity DataIC50:  326nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382320(CHEMBL2024687)
Affinity DataIC50:  695nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50382326(CHEMBL2024692)
Affinity DataIC50:  708nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564607(CHEMBL4799736)
Affinity DataIC50:  748nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564619(CHEMBL4795745)
Affinity DataIC50:  972nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564596(CHEMBL4781452)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  5.97E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564606(CHEMBL4783147)
Affinity DataIC50:  6.69E+3nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  7.83E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM102618(LDN-212854)
Affinity DataIC50:  9.28E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564597(CHEMBL4794175)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50564600(CHEMBL4784607)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed