TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of 0.1 mg/mL BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in presence of bovine serum albuminMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of rat pol beta using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate after 60 minsMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assayMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 60 minsMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair