Compile Data Set for Download or QSAR
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Found 13 of ic50 data for polymerid = 578
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450824(CHEMBL4203009)
Affinity DataIC50:  69nMAssay Description:Inhibition of ABAD (unknown origin) assessed as residual activity using acetoacetyl-CoA in presence of NADH by spectrophotometric assay relative to c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450824(CHEMBL4203009)
Affinity DataIC50:  92nMAssay Description:Inhibition of ABAD (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232928(US9346839, 9 | US9738668, Compound 9)
Affinity DataIC50:  7.20E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232926(US9346839, 7 | US9738668, Compound 7)
Affinity DataIC50:  9.90E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataIC50:  1.96E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataIC50:  3.41E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataIC50:  5.27E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232929(US9346839, 10 | US9738668, Compound 10)
Affinity DataIC50:  1.25E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232925(US9346839, 6 | US9738668, Compound 6)
Affinity DataIC50:  1.65E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataIC50:  2.59E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232924(US9346839, 5 | US9738668, Compound 5)
Affinity DataIC50:  3.35E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataIC50:  3.41E+5nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM232931(US9346839, 15 | US9738668, Compound 15)
Affinity DataIC50:  1.26E+6nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent