Compile Data Set for Download or QSAR
maximum 50k data
Found 86 of ic50 data for polymerid = 8334
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198005(US9221790, 15)
Affinity DataIC50:  0.00200nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197995(US9221790, 5)
Affinity DataIC50:  0.00500nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197993(US9221790, 3)
Affinity DataIC50:  0.0390nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197997(US9221790, 7)
Affinity DataIC50:  0.0670nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198000(US9221790, 10)
Affinity DataIC50:  0.0760nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197996(US9221790, 6)
Affinity DataIC50:  0.103nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198003(US9221790, 13)
Affinity DataIC50:  0.134nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197992(US9221790, 2)
Affinity DataIC50:  0.164nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197998(US9221790, 8)
Affinity DataIC50:  0.182nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM29525(3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...)
Affinity DataIC50:  0.210nMAssay Description:Antagonist activity at human 5HT4ER expressed in CHO cells assessed as reduction in cAMP levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197991(US9221790, 1)
Affinity DataIC50:  0.226nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197994(US9221790, 4)
Affinity DataIC50:  0.229nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM197999(US9221790, 9)
Affinity DataIC50:  0.267nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataIC50:  0.362nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198004(US9221790, 14)
Affinity DataIC50:  0.375nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198002(US9221790, 12)
Affinity DataIC50:  0.421nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM198001(US9221790, 11)
Affinity DataIC50:  0.454nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM85026(N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...)
Affinity DataIC50:  0.630nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50398963(CHEMBL2179674)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at human 5HT4ER expressed in CHO cells assessed as reduction in cAMP levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50398964(CHEMBL2179707)
Affinity DataIC50:  9.80nMAssay Description:Antagonist activity at human 5HT4ER expressed in CHO cells assessed as reduction in cAMP levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50530423(CHEMBL4451349)
Affinity DataIC50: <10nMAssay Description:Antagonist activity at 5-HT4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50530423(CHEMBL4451349)
Affinity DataIC50: <10nMAssay Description:Antagonist activity at 5-HT4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50515600(CHEMBL4580044)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50301927(CHEMBL1748 | Norcisapride)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50056415(2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzo...)
Affinity DataIC50:  49nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142926(CHEMBL3759759)
Affinity DataIC50:  52nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142909(CHEMBL3759928)
Affinity DataIC50:  66nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142929(CHEMBL3758309)
Affinity DataIC50:  68nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142928(CHEMBL3758976)
Affinity DataIC50:  73nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142921(CHEMBL3758433)
Affinity DataIC50:  78nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50515599(CHEMBL4457426)
Affinity DataIC50:  101nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50019523(CHEMBL3291078)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142920(CHEMBL3759944)
Affinity DataIC50:  118nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142923(CHEMBL3758641)
Affinity DataIC50:  134nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142919(CHEMBL3759860)
Affinity DataIC50:  134nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142925(CHEMBL3758674)
Affinity DataIC50:  155nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142918(CHEMBL3759546)
Affinity DataIC50:  178nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142904(CHEMBL3759969)
Affinity DataIC50:  190nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50019524(CHEMBL3291079)
Affinity DataIC50:  195nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50019520(CHEMBL3291075)
Affinity DataIC50:  203nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  323nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142907(CHEMBL3759259)
Affinity DataIC50:  329nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142922(CHEMBL3758398)
Affinity DataIC50:  377nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50019525(CHEMBL3291080)
Affinity DataIC50:  453nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataIC50:  483nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142906(CHEMBL3759348)
Affinity DataIC50:  493nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142910(CHEMBL3758945)
Affinity DataIC50:  560nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142903(CHEMBL3759362)
Affinity DataIC50:  592nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Dong-A Pharm.

US Patent
LigandPNGBDBM50142924(CHEMBL3758397)
Affinity DataIC50:  593nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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