Affinity DataKd: 2.60nMAssay Description:Binding affinity to mouse histamine H3 receptor overexpressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to histamine H3 receptor in wild type mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Displacement of [3H]Methylhistamine from human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 7.90nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 6.31nMAssay Description:Antagonist activity at histamine H3 receptor in rat cortical hemispheres assessed as inhibition of forskolin stimulated cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 1.82nMAssay Description:Antagonist activity at histamine H3 receptor in rat cortical hemispheres assessed as inhibition of forskolin stimulated cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 26.3nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 3.98nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 5.01nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 11.5nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 6.92nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 3.72nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 9.55nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 3.55nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 4.17nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
Affinity DataKd: 25.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 3.98nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 7.94nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 5.01nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 1.26nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 50.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 6.17nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 0.158nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 61.7nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 0.340nMAssay Description:Binding affinity to rat brain histamine H3 receptor after 1 hr by gamma countingMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to rat histamine H3 receptor low affinity site after 1 hr by Schard plot analysisMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 25.1nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 39.8nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 15.8nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 19.9nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 316nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKd: 12.6nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair