TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 4.30E+4nMAssay Description:Binding affinity to biotinylated human RAGE by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to recombinant human RAGE assessed as dissociation constantMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Rattus norvegicus)
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to Wistar rat His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 15nMAssay Description:Binding affinity to human RAGE domain V by autoradiographyMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 6nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 3nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Inhibition of amyloid beta (1 to 42) binding to RAGE domain V (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 2.40E+7nMAssay Description:Inhibition of amyloid beta binding to human RAGE domain V (Met1 to Ala 344 residues) expressed in HEK293 cells after 10 mins by MST assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 32nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 0.550nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 123nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.40nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 6.5nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: >1.00E+5nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 75nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 78nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 12.7nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 219nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 22.3nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataKd: 257nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair