Compile Data Set for Download or QSAR
maximum 50k data
Found 107 of kd data for polymerid = 9678,49000359,49000360,49000363,50000829
LigandPNGBDBM50281902((R)-2-[2-(10H-Anthracen-9-ylidene)-ethyl]-1-methyl...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281903((S)-2-[(E)-2-(9,10-Dihydro-anthracen-9-yl)-vinyl]-...)
Affinity DataKd:  21nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKd:  2.70nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKd:  3nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50031098((E)-(R)-2-Hydroxy-5-iodo-2-phenyl-pent-4-enoic aci...)
Affinity DataKd:  41nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-QNB as radioligand from rat heart tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50453895(CHEMBL2111842)
Affinity DataKd:  0.430nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-QNB as radioligand from rat heart tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50450592(CHEMBL558910)
Affinity DataKd:  0.200nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-QNB as radioligand from rat heart tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  4.40E+3nMAssay Description:Dissociation constant of the compound for human Muscarinic acetylcholine receptor M2 was determined.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  1.21E+3nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  3nMAssay Description:Dissociation constant for the blocking of cardiac muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  1.21E+3nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281906(2-[(E)-2-(9,9a-Dihydro-4aH-xanthen-9-yl)-vinyl]-1-...)
Affinity DataKd:  25nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281905(2-[3-(10H-Anthracen-9-ylidene)-propyl]-1-methyl-pi...)
Affinity DataKd:  7.60nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281908(2-((E)-2-Anthracen-9-yl-vinyl)-1-methyl-piperidine...)
Affinity DataKd:  635nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281909((R)-2-[(E)-2-(9,10-Dihydro-anthracen-9-yl)-vinyl]-...)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  9.10nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281904(2-[(E)-3-(9,10-Dihydro-anthracen-9-yl)-allyl]-1-me...)
Affinity DataKd:  23nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281907((S)-2-[2-(10H-Anthracen-9-ylidene)-ethyl]-1-methyl...)
Affinity DataKd:  35nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284319((2S,6R)-1,2-Dimethyl-6-[(E)-2-((3S,3aR,4R,4aS,8aR,...)
Affinity DataKd:  353nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284321(Acetic acid (S)-1-{(1R,2R,3S,4aR,8aS)-3-acetoxymet...)
Affinity DataKd:  249nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284320((S)-1-{(1R,2R,3S,4aR,8aS)-1-[(E)-2-((2R,6S)-1,6-Di...)
Affinity DataKd:  293nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284322(Acetic acid (1R,3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((...)
Affinity DataKd:  89nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284323(2,2-Dimethyl-propionic acid (1R,3S,3aR,4R,4aS,8aR,...)
Affinity DataKd:  464nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  10nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50284324((1S,3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((2R,6S)-1,6-D...)
Affinity DataKd:  96nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50015721(3-Hydroxy-2-phenyl-propionic acid 8-iminomethyl-8-...)
Affinity DataKd:  1.60nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015719(3-Hydroxy-2-phenyl-propionic acid 9-iminomethyl-3-...)
Affinity DataKd:  10nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015724(3-Hydroxy-2-phenyl-propionic acid 9-(1-imino-ethyl...)
Affinity DataKd:  6.70nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015727(7-(3-Hydroxy-2-phenyl-propionyloxy)-9,9-dimethyl-3...)
Affinity DataKd:  0.870nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015726(3-Hydroxy-2-phenyl-propionic acid 9-carbamimidoyl-...)
Affinity DataKd:  23nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015723(3-Hydroxy-2-phenyl-propionic acid 8-carbamimidoyl-...)
Affinity DataKd:  11nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015722(3-Hydroxy-2-phenyl-propionic acid 8-(1-imino-ethyl...)
Affinity DataKd:  10nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015725(9-Butyl-7-(3-hydroxy-2-phenyl-propionyloxy)-9-meth...)
Affinity DataKd:  220nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015728(3-(3-Hydroxy-2-phenyl-propionyloxy)-8,8-dimethyl-8...)
Affinity DataKd:  2.70nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M2 in rat heart was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50031098((E)-(R)-2-Hydroxy-5-iodo-2-phenyl-pent-4-enoic aci...)
Affinity DataKd:  30nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-QNB as radioligand from rat heart tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50083651((S)-3-Hydroxy-2-(2-tetradecanoylamino-acetylamino)...)
Affinity DataKd:  0.150nMAssay Description:Binding of [3H]-QNB to HM2 receptor was evaluated by saturation binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50083652(CHEMBL112297 | Hexadecanoic acid (S)-2-benzyloxyca...)
Affinity DataKd:  1.80nMAssay Description:Binding of [3H]QNB to HM2 receptor was evaluated by saturation binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413106(CHEMBL538360)
Affinity DataKd:  5.01nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413107(CHEMBL550885)
Affinity DataKd:  5.01nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413108(CHEMBL540145)
Affinity DataKd:  1.58nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413109(CHEMBL553448)
Affinity DataKd:  0.0501nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413110(CHEMBL540148)
Affinity DataKd:  0.200nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413111(CHEMBL540401)
Affinity DataKd:  6.31nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413112(CHEMBL540146)
Affinity DataKd:  6.31nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413113(CHEMBL555706)
Affinity DataKd:  3.98nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412340(CHEMBL540359)
Affinity DataKd:  1nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412728(CHEMBL521523)
Affinity DataKd:  5.01nMAssay Description:Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379278(CHEMBL2011501)
Affinity DataKd:  700nMAssay Description:Orthosteric antagonist activity at M2 receptor by AS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  6.90nMAssay Description:Dissociation constant for the blocking of heart muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  4.60nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
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