Affinity DataKi: 0.320nMAssay Description:Displacement of [125I]-BH-JMV-179 from wild type human CCK1 receptor expressed in COS7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity of the compound against CCK-A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.72nMAssay Description:Displacement of [125I](S)-1-(3-iodophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea from human CCK1 receptor express...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]-SR-27897 from wild type human CCK1 receptor expressed in COS7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(Mus musculus)
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity of the compound in Cholecystokinin type A receptor binding assay (iv) in miceMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nM EC50: 2.50E+3nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Tested for its selectivity against human Cholecystokinin type A receptor isolated from a human gallbladder cDNA library and stably transfected into a...More data for this Ligand-Target Pair
Affinity DataKi: 10.4nMAssay Description:Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]L-364718 from human recombinant CCK1 receptor expressed in CHOK1 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]CCK-8(SO3) from human CCK1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Tested for its selectivity against human Cholecystokinin type A receptor isolated from a human gallbladder cDNA library and stably transfected into a...More data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 59.8nMAssay Description:Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 63.1nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Tested for its selectivity against human Cholecystokinin type A receptor isolated from a human gallbladder cDNA library and stably transfected into a...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 98nM EC50: 300nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Displacement of [125I](S)-1-(3-iodophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea from human CCK1 receptor express...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [125I]-CCK-8S from human CCK-1R after 100 mins by liquid scintillation countingMore data for this Ligand-Target Pair