Compile Data Set for Download or QSAR
Report error Found 5 of koff data for polymerid = 1036,1095,1874,1875,1876,1877,1880,1883,1884,1885,1889,1910,1919,4105,4882,6537,8812
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKon:  12M-1s-1Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50022831(6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143)
Affinity DataKon:  25M-1s-1Assay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKon:  26M-1s-1Assay Description:Dissociation constant at Val-31(Kon)of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKon:  26M-1s-1Assay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50022831(6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143)
Affinity DataKon:  35M-1s-1Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed