Compile Data Set for Download or QSAR
Report error Found 11 of koff data for polymerid = 10485,10592,10684,10485,10592,10684
TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  4.40nM Kon:  0.0000900M-1s-1 Koff:  2.00E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKd:  5.20nM Kon:  0.000100M-1s-1 Koff:  2.00E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243479BDBM243479(US9427440, 27)
Affinity DataKon:  0.00380M-1s-1 Koff:  9.50E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243476BDBM243476(US9427440, 24)
Affinity DataKon:  0.00370M-1s-1 Koff:  4.80E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243477BDBM243477(US9427440, 25)
Affinity DataKon:  0.000310M-1s-1 Koff:  2.90E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243469BDBM243469(US9427440, 17)
Affinity DataKon:  0.000160M-1s-1 Koff:  8.70E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243456BDBM243456(US9427440, 1)
Affinity DataKon:  0.0000900M-1s-1 Koff:  2.00E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243480BDBM243480(US9427440, 28)
Affinity DataKon:  0.0000660M-1s-1 Koff:  7.30E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243468BDBM243468(US9427440, 16)
Affinity DataKon:  0.0000360M-1s-1 Koff:  2.20E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243470BDBM243470(US9427440, 18)
Affinity DataKon:  0.0000480M-1s-1 Koff:  2.00E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 243481BDBM243481(US9427440, 38)
Affinity DataKon:  0.0000410M-1s-1 Koff:  5.30E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent