TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 0.300nM Kd: 0.0100nM Kon: 0.000300M-1s-1 Koff: 3.00E+6s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 13nM Kd: 1.70nM Kon: 0.0200M-1s-1 Koff: 1.20E+7s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 320nM Kd: 71nM Kon: 0.100M-1s-1 Koff: 1.40E+6s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 845nM Kd: 167nM Kon: 0.200M-1s-1 Koff: 1.20E+6s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair