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Report error Found 5 Enz. Inhib. hit(s) for PDB: 1XM6
LigandPNGBDBM14772((R,S)-Mesopram | 5-(4-methoxy-3-propoxy-phenyl)-5-...)
Affinity DataIC50:  420nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50308512((5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-ox...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50308512((5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-ox...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50308512((5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-ox...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
LigandPNGBDBM14772((R,S)-Mesopram | 5-(4-methoxy-3-propoxy-phenyl)-5-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair