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Report error Found 2 Enz. Inhib. hit(s) for PDB: 2C3L
TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM16590(2-(1H-indazol-3-yl)-1H-1,3-benzodiazole | 3-(1H-be...)
Affinity DataKi:  8.58E+3nM ΔG°:  -29.4kJ/molepH: 7.5 T: 30°CAssay Description:For Ki determinations a matrix of inhibitor and substrate concentrations were tested. Inhibitor concentrations were tested from four times IC50 with ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM16590(2-(1H-indazol-3-yl)-1H-1,3-benzodiazole | 3-(1H-be...)
Affinity DataIC50:  6.30E+3nMpH: 7.5 T: 30°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor compound in the presence ATP/[gamma-33P] ATP. 33P ...More data for this Ligand-Target Pair