Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3K99
TargetHeat shock protein HSP 90-alpha [1-236](Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM227591(PA7)
Affinity DataKd:  27.3nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM227591(PA7)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)