Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 7 Enz. Inhib. hit(s) for PDB: 2AA6
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at mineralocorticoid receptor (hMR)More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  14nMAssay Description:Antagonistic activity was determined in Human mineralocorticoid receptor(hMR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50: >14nMAssay Description:Inhibitory activity against human mineralocorticoid receptor (hMR)More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against human Mineralocorticoid receptorMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 10e-9 M aldosterone activity in CV-1 cells expressing mineralocorticoid receptorMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataKd:  0.390nMAssay Description:Affinity for recombinant Mineralocorticoid receptorMore data for this Ligand-Target Pair