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Report error Found 3 Enz. Inhib. hit(s) for PDB: 3EQM
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM8592((2R,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50:  300nMpH: 7.5 T: 37°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM50025428(10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataKi:  20nMAssay Description:Binding affinity for aromatase cytochrome P45019A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM50025428(10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataIC50:  300nMAssay Description:In vitro competetitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair