Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) for PDB: 2F89
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against the human recombinant FPPSase (Farnesyl diphosphate) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 353nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant FPP synthase expressed in Escherichia coli S100 using FPP and IPP as substrates preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataKi:  55.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM12581(JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...)
Affinity DataKi:  331nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)