Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) for PDB: 4Q9Z
TargetProtein kinase C theta type(Homo sapiens (Human))
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Show SMILES C[C@H]1N2C(COc3cc(C)c(NC4CNC4)cc23)=NNC1=O
Show InChI InChI=1S/C15H19N5O2/c1-8-3-13-12(4-11(8)17-10-5-16-6-10)20-9(2)15(21)19-18-14(20)7-22-13/h3-4,9-10,16-17H,5-7H2,1-2H3,(H,19,21)/t9-/m1/s1
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049430(CHEMBL3356464)
Show SMILES CC1N2C(COc3cc(C)c(NC4CNC4)cc23)=NNC1=O
Show InChI InChI=1S/C15H19N5O2/c1-8-3-13-12(4-11(8)17-10-5-16-6-10)20-9(2)15(21)19-18-14(20)7-22-13/h3-4,9-10,16-17H,5-7H2,1-2H3,(H,19,21)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair