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Report error Found 3 Enz. Inhib. hit(s) for PDB: 3GXL
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50:  90nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair