Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) for PDB: 3II5
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Show SMILES CN(C)Cc1ccc(cc1)-c1cnn2c(ccnc12)-c1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1
Show InChI InChI=1S/C29H24F3N5O/c1-36(2)18-19-9-11-20(12-10-19)25-17-34-37-26(13-14-33-27(25)37)21-5-4-8-24(16-21)35-28(38)22-6-3-7-23(15-22)29(30,31)32/h3-17H,18H2,1-2H3,(H,35,38)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair