Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
3D Structure (crystal)Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory activity against human 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human 11beta-HSD1 by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of 11beta-HSD1 in human microsomes by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
