Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) for PDB: 2YIS
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50361467(CHEMBL1938400)
Show SMILES CC(C)(C)c1cc(NC(=O)NCc2ccccc2Sc2ccc3nnc(-c4ccccc4SCCO)n3c2)n(n1)-c1ccc(O)c(Cl)c1
Show InChI InChI=1S/C35H34ClN7O3S2/c1-35(2,3)30-19-32(43(41-30)23-12-14-27(45)26(36)18-23)38-34(46)37-20-22-8-4-6-10-28(22)48-24-13-15-31-39-40-33(42(31)21-24)25-9-5-7-11-29(25)47-17-16-44/h4-15,18-19,21,44-45H,16-17,20H2,1-3H3,(H2,37,38,46)
Affinity DataKd:  0.00100nMAssay Description:Binding affinity to human p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair