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Report error Found 2 Enz. Inhib. hit(s) for PDB: 3TJC
TargetTyrosine-protein kinase JAK2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361829(CHEMBL1938643)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged JAK2 expressed in Sf9 cells using Biotin-LC-EQEDEPEGDYFEWLE as substrate after 90 mins by TR-FR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361829(CHEMBL1938643)
Affinity DataIC50:  3.94E+3nMAssay Description:Inhibition of TEL-fused JAK2 expressed in Ba/F3 cells assessed as inhibition of STAT5 phosphorylation after 60 mins by AlphaScreen assayMore data for this Ligand-Target Pair