Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5KHX
TargetTyrosine-protein kinase JAK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50243850(CHEMBL4100431)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human JAK1 using 5'FAM-KKSRGDYMTMQID as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
LigandPNGBDBM50243850(CHEMBL4100431)
Affinity DataIC50:  750nMAssay Description:Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFNalpha induced STAT3 phosphorylation preincubated for 45 mins followed by IFN...More data for this Ligand-Target Pair