Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) for PDB: 5TOE
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262397(CHEMBL4074103)
Show SMILES N#Cc1ccnc2[nH]c(cc12)-c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C18H17N5/c19-12-14-5-6-21-18-16(14)11-17(22-18)13-1-3-15(4-2-13)23-9-7-20-8-10-23/h1-6,11,20H,7-10H2,(H,21,22)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in full length human BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair