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Report error Found 4 Enz. Inhib. hit(s) for PDB: 5ZJ6
TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)
Affinity DataIC50:  0.427nMAssay Description:Inhibition of HCK (75 to 526 residues) (unknown origin) expressed in Sf9 insect cells after 120 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of human HCK (81 to 526 residues) expressed in Sf9 insect cells after 120 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)
Affinity DataIC50:  3.30nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair