Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) for PDB: 4E26
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50420775(CHEMBL581146 | TCMDC-125324)
Show SMILES Oc1c(cc(Cl)c2cccnc12)C(Nc1ccccn1)c1ccco1
Show InChI InChI=1S/C19H14ClN3O2/c20-14-11-13(19(24)18-12(14)5-3-9-22-18)17(15-6-4-10-25-15)23-16-7-1-2-8-21-16/h1-11,17,24H,(H,21,23)
Affinity DataIC50: 800nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair