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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) for PDB:
4ISE
Target
Hexokinase-4
(Homo sapiens (Human))
Takeda California Inc
Curated by
ChEMBL
Ligand
BDBM50431763
(CHEMBL2346889)
Show SMILES
Fc1ccc2ncn([C@@H](CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI
InChI=1S/C20H21FN4O2S/c21-14-6-7-16-15(11-14)19(27)25(12-23-16)17(10-13-4-2-1-3-5-13)18(26)24-20-22-8-9-28-20/h6-9,11-13,17H,1-5,10H2,(H,22,24,26)/t17-/m0/s1
Affinity Data
EC50: 4.00E+3nM
Assay Description:
Activation of glucokinase (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BDB Entry
PubMed
PDB
3D Structure (crystal)