Affinity DataKi: 0.100nMAssay Description:Inhibition of SERCA1a (unknown origin) ATPase activityMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rabbit sarcoplasmic reticulum calcium ATPase by ATP regeneration assayMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of rabbit skeletal muscle SERCA1 assessed as reduction in calcium uptake preincubated for 10 mins followed by ATP addition and measured af...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Binding affinity to SERCA1a in sarcoplasmic reticulum vesicles of rabbit skeletal muscle after 2.5 to 6 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
