Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) for PDB: 4G9R
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.

Curated by ChEMBL
LigandPNGBDBM50430022(CHEMBL2144069)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.

Curated by ChEMBL
LigandPNGBDBM50430022(CHEMBL2144069)
Affinity DataIC50:  27nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.

Curated by ChEMBL
LigandPNGBDBM50430022(CHEMBL2144069)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of human recombinant N-terminus His-tagged BRAF expressed in Sf9 cells coexpressing CDC37 using biotinylated MEK as substrate and MgCl2 in...More data for this Ligand-Target Pair