Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6T3C
LigandPNGBDBM413450(US10407446, Example 3 | 7-methyl-2-((7-methyl-[1,2...)
Affinity DataIC50: 52nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant full-length human His-tagged p110gamma expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM413450(US10407446, Example 3 | 7-methyl-2-((7-methyl-[1,2...)
Affinity DataIC50: 363nMAssay Description:Inhibition of human PI3Kgamma by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM413450(US10407446, Example 3 | 7-methyl-2-((7-methyl-[1,2...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264 cells assessed as reduction in C5a anaphylatoxin trifluoroacetate salt-induced AKT phosphorylation at T208 re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)