Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with Target = 'Enoyl-ACP reductase'
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50329257(2-Hexadecynoic acid | CHEMBL1269411)
Affinity DataKi:  2.58E+3nMAssay Description:Non-competitive inhibition of Plasmodium falciparum FabI using NADH as cofactor by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50329257(2-Hexadecynoic acid | CHEMBL1269411)
Affinity DataKi:  2.90E+3nMAssay Description:Non-competitive inhibition of Plasmodium falciparum FabI using crotonyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25418(2-(2,4-dichlorophenoxy)-5-(4-fluorophenyl)phenol |...)
Affinity DataIC50:  38nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25403(4‐(2,4‐dichlorophenoxy)‐3‐...)
Affinity DataIC50:  49nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25419(5-benzyl-2-(2,4-dichlorophenoxy)phenol | Triclosan...)
Affinity DataIC50:  71nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  73nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25420(2-(2,4-dichlorophenoxy)-5-(2-phenylethyl)phenol | ...)
Affinity DataIC50:  76nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25407(2‐(2,4‐dichlorophenoxy)‐5‐...)
Affinity DataIC50:  110nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25412(2-(2,4-dichlorophenoxy)-5-(3-methylbutyl)phenol | ...)
Affinity DataIC50:  120nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25402(2-(2,4-dichlorophenoxy)-5-phenylphenol | Triclosan...)
Affinity DataIC50:  140nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25410(2-(2,4-dichlorophenoxy)-5-(2-methylpropyl)phenol |...)
Affinity DataIC50:  180nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25417(2-(2,4-dichlorophenoxy)-5-(4-methylphenyl)phenol |...)
Affinity DataIC50:  190nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25401(2-(2,4-dichlorophenoxy)-5-methylphenol | Triclosan...)
Affinity DataIC50:  200nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25408(2-(2,4-dichlorophenoxy)-5-propylphenol | Triclosan...)
Affinity DataIC50:  210nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25416(2-(2,4-dichlorophenoxy)-5-(3-methylphenyl)phenol |...)
Affinity DataIC50:  230nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25411(2-(2,4-dichlorophenoxy)-5-(2-methylbutyl)phenol | ...)
Affinity DataIC50:  290nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25415(3-chloro-4-[2-hydroxy-4-(2-methylphenyl)phenoxy]be...)
Affinity DataIC50:  410nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25414(2-(2,4-dichlorophenoxy)-5-(2-methylphenyl)phenol |...)
Affinity DataIC50:  440nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25421(2-(2,4-dichlorophenoxy)-5-(3-phenylpropyl)phenol |...)
Affinity DataIC50:  440nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25409(5-butyl-2-(2,4-dichlorophenoxy)phenol | Triclosan ...)
Affinity DataIC50:  480nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25413(5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol...)
Affinity DataIC50:  530nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25427(3-chloro-4-[2-hydroxy-4-(pyridin-4-ylmethyl)phenox...)
Affinity DataIC50:  530nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25425(2-(2,4-dichlorophenoxy)-5-(pyridin-2-ylmethyl)phen...)
Affinity DataIC50:  640nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50:  700nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25426(2-(2,4-dichlorophenoxy)-5-(pyridin-3-ylmethyl)phen...)
Affinity DataIC50:  840nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25424(3-chloro-4-[2-hydroxy-4-(pyridin-4-yl)phenoxy]benz...)
Affinity DataIC50:  2.80E+3nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50349974(CHEMBL1812485)
Affinity DataIC50:  7.69E+3nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25405(4-(2,4-dichlorophenoxy)-3-hydroxybenzamide | Tricl...)
Affinity DataIC50:  2.10E+4nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25423(2-(2,4-dichlorophenoxy)-5-(pyridin-3-yl)phenol | T...)
Affinity DataIC50:  3.30E+4nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50240896(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H...)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50349976(ISOWIGHTEONE)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataIC50: >1.00E+5nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM25404(2-(2,4-dichlorophenoxy)-5-(2H-1,2,3,4-tetrazol-5-y...)
Affinity DataIC50: >1.00E+5nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of London

Curated by ChEMBL
LigandPNGBDBM50349975(CHEMBL1812593)
Affinity DataIC50:  2.48E+5nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed