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Found 7 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1207,D168A]'
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  25nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50:  98nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  312nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  321nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50:  508nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50:  1.15E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50:  2.55E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent