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Found 3 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010,S282T]'
TargetGenome polyprotein [2420-3010,S282T](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Gilead Pharmasset

US Patent
LigandPNGBDBM240845(US9394331, 140 | US9394331, 52)
Affinity DataIC50:  5.67E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010,S282T](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Gilead Pharmasset

US Patent
LigandPNGBDBM240844(US9394331, 136 | US9394331, 48)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010,S282T](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Gilead Pharmasset

US Patent
LigandPNGBDBM240843(US9394331, 137 | US9394331, 49)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent