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Found 31 Enz. Inhib. hit(s) with Target = 'Neutral alpha-glucosidase AB'
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  14nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 8.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280031((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...)
Affinity DataKi:  15nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  160nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280029((2R,3R,4R,5S)-2-(1-Hydroxy-propyl)-piperidine-3,4,...)
Affinity DataKi:  3.00E+3nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280030((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...)
Affinity DataKi:  8.00E+3nMpH: 8.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280030((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...)
Affinity DataKi:  1.50E+4nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  2.10E+4nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  2.30E+4nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280030((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...)
Affinity DataKi:  2.90E+4nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280030((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...)
Affinity DataKi:  4.70E+4nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280030((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...)
Affinity DataKi:  4.70E+4nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on Asp. Wentii beta Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280029((2R,3R,4R,5S)-2-(1-Hydroxy-propyl)-piperidine-3,4,...)
Affinity DataKi:  6.00E+4nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on almonds beta Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  4.10E+5nMAssay Description:Tested for competitive inhibition of golgi alpha mannosidase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  4.60E+5nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280031((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...)
Affinity DataKi: >1.50E+6nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280032((2R,3R,4R,5S)-2-Methyl-piperidine-3,4,5-triol | 1,...)
Affinity DataKi:  1.56E+6nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280029((2R,3R,4R,5S)-2-(1-Hydroxy-propyl)-piperidine-3,4,...)
Affinity DataKi:  2.00E+6nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  1.30E+3nMAssay Description:Tested for competitive inhibition of endoplasmic reticulum alpha-glucosidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  2.50E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (Golgi I) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50407255(CHEMBL2114189)
Affinity DataIC50:  4.60E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi II) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50407255(CHEMBL2114189)
Affinity DataIC50:  5.30E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi I) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50407255(CHEMBL2114189)
Affinity DataIC50:  8.40E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase was determined in rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50407255(CHEMBL2114189)
Affinity DataIC50:  8.40E+4nMAssay Description:Concentration that causes 50% inhibition of soluble mammalian alpha-mannosidase in rat liver; NI is less than 50 % inhibition at 1000 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50407255(CHEMBL2114189)
Affinity DataIC50:  1.10E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (lysosomal) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  2.10E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase was determined in rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  3.20E+5nMAssay Description:Concentration that causes 50% inhibition of soluble mammalian alpha-mannosidase in rat liver. NI is less than 50 % inhibition at 1000 micro MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  5.00E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (Golgi II) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  5.70E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (lysosomal) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataIC50:  8.00E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi II) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataIC50:  1.00E+6nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (lysosomal) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase AB(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)
Affinity DataIC50:  1.00E+6nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi II) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed