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Found 29 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src [251-533]'
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234848(US9353116, 5)
Affinity DataIC50:  899nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234843(US9353116, 3)
Affinity DataIC50:  1.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234861(US9353116, 20)
Affinity DataIC50:  2.17E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234845(US9353116, 1)
Affinity DataIC50:  2.32E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234852(US9353116, 10)
Affinity DataIC50:  3.08E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234849(US9353116, 6)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234860(US9353116, 19 | US9353116, Fig. 16, Compound 1)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234859(US9353116, 18)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234858(US9353116, 17)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234857(US9353116, 16)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234856(US9353116, 15)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234855(US9353116, 14)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234844(US9353116, 13)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234854(US9353116, 12)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234846(US9353116, 2)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234847(US9353116, 4)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234850(US9353116, 7)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234851(US9353116, 8)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50403061(CHEMBL2216823 | US9353116, 9)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234853(US9353116, 11)
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185671(DAS-DFGO-II)
Affinity DataKd:  2.70nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  0.0700nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185672(DAS-CHO-I)
Affinity DataKd:  15nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185670(DAS-DFGO-I | N-(2-chloro-6-methylphenyl)-2-[[6-[4-...)
Affinity DataKd:  0.530nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185675(DAS-BODIPY)
Affinity DataKd:  0.5nMpH: 8.0Assay Description:Reaction volumes of 50 μL were used in 96-well plates. Buffer A (1×, 34 μL; 100 mM Tris, pH 8, 10 mM MgCl2) was added to a single row, foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataKd:  0.700nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against phospho...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185674(4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...)
Affinity DataKd:  11nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against phospho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185676(DAS-DFGO-II-BODIPY)
Affinity DataKd:  2.80nMpH: 8.0Assay Description:Reaction volumes of 50 μL were used in 96-well plates. Buffer A (1×, 34 μL; 100 mM Tris, pH 8, 10 mM MgCl2) was added to a single row, foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents Of The University Of California

US Patent
LigandPNGBDBM185673(DAS-CHO-II)
Affinity DataKd:  1.70nMAssay Description:Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed