Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1 [1-322]'
TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataKi:  2.40E+3nM IC50:  4.80E+3nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM223197(2-Bromo-N-[3'-(1,1-dioxido-4-oxo-1,2,5-thiadia...)
Affinity DataKi:  2.70E+4nM IC50:  5.40E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM223198(N-[3'-(1,1-Dioxido-4-oxo-1,2,5-thiadiazolidin-...)
Affinity DataKi:  3.20E+4nM IC50:  6.40E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM223199(5-(4-Methyl[1,1'-biphenyl]-3-yl)-1,2,5-thiadia...)
Affinity DataKi:  3.85E+4nM IC50:  7.70E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed