Compile Data Set for Download or QSAR
Report error Found 6373 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1'
LigandPNGBDBM29842(N-(Pyridin-2-yl) arylsulfonamide, 2)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29845(N-(Pyridin-2-yl) arylsulfonamide, 5)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29846(N-(Pyridin-2-yl) arylsulfonamide, 6)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29847(N-(Pyridin-2-yl) arylsulfonamide, 7)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29848(N-(Pyridin-2-yl) arylsulfonamide, 8)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29851(N-(Pyridin-2-yl) arylsulfonamide, 13)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29852(N-(Pyridin-2-yl) arylsulfonamide, 14)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29853(N-(Pyridin-2-yl) arylsulfonamide, 15)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29844(N-(Pyridin-2-yl) arylsulfonamide, 4)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM29855(N-(Pyridin-2-yl) arylsulfonamide, 17)
Affinity DatapH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50435691(CHEMBL2391968)
Affinity DataKd:  11nMAssay Description:Binding affinity to human microsomal 11beta-HSD1 by radiometric competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382819(CHEMBL2023584)
Affinity DataEC50:  37nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50185127(30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-be...)
Affinity DataEC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382826(CHEMBL2023422)
Affinity DataEC50:  60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382828(CHEMBL2023424)
Affinity DataEC50:  55nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382827(CHEMBL2023423)
Affinity DataEC50:  90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382830(CHEMBL2023428)
Affinity DataEC50:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382831(CHEMBL2023431)
Affinity DataEC50:  283nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382821(CHEMBL2023586)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382815(CHEMBL2023426)
Affinity DataEC50:  55nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432932(CHEMBL2377214)
Affinity DataEC50:  184nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432940(CHEMBL2377205)
Affinity DataEC50:  21nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432941(CHEMBL2377204)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382824(CHEMBL2023421)
Affinity DataEC50:  802nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM29864(N-(Pyridin-2-yl) arylsulfonamide, 26)
Affinity DataEC50:  5nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50432930(CHEMBL2377216)
Affinity DataEC50:  51nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382827(CHEMBL2023423)
Affinity DataEC50:  210nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382819(CHEMBL2023584)
Affinity DataEC50:  121nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432937(CHEMBL2377208)
Affinity DataEC50:  194nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM29860(N-(Pyridin-2-yl) arylsulfonamide, 22)
Affinity DataEC50:  53nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382822(CHEMBL2023587)
Affinity DataEC50:  2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382815(CHEMBL2023426)
Affinity DataEC50:  70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382831(CHEMBL2023431)
Affinity DataEC50:  17nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432927(CHEMBL2377219)
Affinity DataEC50:  604nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432936(CHEMBL2377209)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382825(CHEMBL2021943)
Affinity DataEC50:  180nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432929(CHEMBL2377217)
Affinity DataEC50:  936nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382816(CHEMBL2023427)
Affinity DataEC50:  3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432931(CHEMBL2377215)
Affinity DataEC50:  1.16E+3nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382817(CHEMBL2023429)
Affinity DataEC50:  258nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382826(CHEMBL2023422)
Affinity DataEC50:  185nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382818(CHEMBL2023430)
Affinity DataEC50:  69nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382830(CHEMBL2023428)
Affinity DataEC50:  401nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432933(CHEMBL2377212)
Affinity DataEC50:  58nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382825(CHEMBL2021943)
Affinity DataEC50:  443nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432938(CHEMBL2377207)
Affinity DataEC50:  1.98E+3nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382829(CHEMBL2023425)
Affinity DataEC50:  47nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50432935(CHEMBL2377210)
Affinity DataEC50:  72nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50382821(CHEMBL2023586)
Affinity DataEC50:  517nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50382828(CHEMBL2023424)
Affinity DataEC50:  84nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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