Compile Data Set for Download or QSAR
Report error Found 684 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 5A'
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585906(CHEMBL5077128)
Affinity DataEC50:  355nMAssay Description:Agonist activity at human 5-HT5A receptor transfected in HTLA cells assessed as increase in beta-arrestin 2 recruitment at 10 uM incubated for 18 to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585907(CHEMBL5082447)
Affinity DataEC50:  3.63E+3nMAssay Description:Agonist activity at human 5-HT5A receptor transfected in HTLA cells assessed as increase in beta-arrestin 2 recruitment at 10 uM incubated for 18 to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422022(CHEMBL101138)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 106nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422016(CHEMBL323334)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422019(CHEMBL321963)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422021(CHEMBL103549)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in HEK293 cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422025(CHEMBL103371)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422029(CHEMBL103388)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422026(CHEMBL320412)
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422023(CHEMBL318571)
Affinity DataIC50: 501nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 501nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422024(CHEMBL319223)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422017(CHEMBL103854)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422028(CHEMBL102548)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422020(CHEMBL103205)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422030(CHEMBL102586)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50330813(3-[(1S,3R)-3-Dimethylaminocyclopentyl]-1H-indole-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422018(CHEMBL102645)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50330441(3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422027(CHEMBL2111620)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...)
Affinity DataIC50: 3.32E+3nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT5A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...)
Affinity DataIC50: 3.32E+3nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT5A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50105109(4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-c...)
Affinity DataIC50: 3.38E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50105107(1-{4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazin-1...)
Affinity DataIC50: 5.52E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50060429((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for the displacement of [3H]5-HT binding to cloned human 5-hydroxytryptamine 5A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50304075(3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50353901(CHEMBL1829958)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10838(3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50353903(CHEMBL1829961)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585909(CHEMBL5089996)
Affinity DataIC50: 4.57E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 32 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585910(CHEMBL5094012)
Affinity DataIC50: 4.90E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 32 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585911(CHEMBL5093969)
Affinity DataIC50: 4.68E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 32 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585912(CHEMBL5075486)
Affinity DataIC50: 5.13E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 32 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585913(CHEMBL5093295)
Affinity DataIC50: 4.57E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 32 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585914(CHEMBL5079273)
Affinity DataIC50: 4.79E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 1 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585915(CHEMBL5082151)
Affinity DataIC50: 4.79E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 1 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585916(CHEMBL5085238)
Affinity DataIC50: 4.79E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 1 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585917(CHEMBL5091270)
Affinity DataIC50: 4.68E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor at 1 uM incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585918(CHEMBL5078567)
Affinity DataIC50: 5.01E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585919(CHEMBL5090584)
Affinity DataIC50: 4.79E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585920(CHEMBL5092524)
Affinity DataIC50: 5.13E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585906(CHEMBL5077128)
Affinity DataIC50: 4.79E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585921(CHEMBL5087602)
Affinity DataIC50: 5.13E+8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 684 total ) | Next | Last >>
Jump to: