Report error Found 3040 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1'
Affinity DataIC50: 0.5nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of GST-tagged human recombinant ALK2 (145 to 509 residues) expressed in baculovirus expression system using casein as substrate in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.36nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
