Compile Data Set for Download or QSAR
Found 2366 Enz. Inhib. hit(s) with Target = 'Alpha-1B adrenergic receptor'
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataKi:  0.00900nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.0380nMAssay Description:Displacement of [3H]prazosin from human recombinant adrenergic alpha-1B receptor expressed in CHO cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328497((11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenzo[...)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274049(CHEMBL342062)
Affinity DataKi:  0.0708nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328500(CHEMBL1259144 | rac-N-((11-(4-Methylpiperazin-1-yl...)
Affinity DataKi:  0.0810nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328496(11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenzo[b...)
Affinity DataKi:  0.0880nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM50328498(1-Methyl-4-[8-(2-methyl-2H-tetrazol-5-ylmethyl)-10...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]prozosin from alpha1b receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50091350(CHEMBL3582270)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1B adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50033109(2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor from hamster clones.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50033109(2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor from hamster clones.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(HAMSTER)
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274053(CHEMBL4126860)
Affinity DataKi:  0.129nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50403649(CYCLAZOSIN)
Affinity DataKi:  0.135nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50487287((+)-CYCLAZOSIN)
Affinity DataKi:  0.135nMAssay Description:Displacement of [3H]prazosin from Homo sapiens (human) alpha1B adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274049(CHEMBL342062)
Affinity DataKi:  0.135nMAssay Description:Compound was tested for binding affinity against human hippocampus Alpha-1B adrenergic receptor using radioligand ([3H]-prazosin) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM50328478(1-Methyl-4-(8-(2-methyl-2H-tetrazol-5-yl)-10,11-di...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]prozosin from alpha1b receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of [3H]- prazosin binding against Alpha-1B adrenergic receptor from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM50328499(1-Methyl-4-[8-(1-methyl-1H-tetrazol-5-ylmethyl)-10...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]prozosin from alpha1b receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274057(CHEMBL4129291)
Affinity DataKi:  0.151nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50475534(CHEMBL198860)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(PIG)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.160nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328488(5-(11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenz...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274054(CHEMBL4128084)
Affinity DataKi:  0.191nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328506((S)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328482(1-Methyl-4-(8-(1-methyl-1H-pyrazol-4-yl)-10,11-dih...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity using [3H]-prazosin as radioligand against adrenoceptor alpha 1b expressed in LTK cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Toray Industries Inc

Curated by ChEMBL
LigandPNGBDBM50487287((+)-CYCLAZOSIN)
Affinity DataKi:  0.209nMAssay Description:Binding affinity to alpha1B adrenoreceptor in Rattus norvegicus (rat) liverMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.210nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]prazosin (0.5 nM) from hamster Alpha-1B adrenergic receptor expressed in rat-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Mus musculus)
University of Dublin

Curated by PDSP Ki Database
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328481(1-Methyl-4-(8-(1-methyl-1H-pyrazol-3-yl)-10,11-dih...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50475533(CHEMBL199080)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50475538(CHEMBL200366)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]prazosin from cloned human ADRA1B expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328486(1-Methyl-4-(8-(pyridin-3-yl)-10,11-dihydrodibenzo[...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328505((R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.280nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1B adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50282204(CHEMBL4161165)
Affinity DataKi:  0.282nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenoceptor expressed in CHO cell membranes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50274052(CHEMBL4127483)
Affinity DataKi:  0.302nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50487286(CHEMBL2261605)
Affinity DataKi:  0.309nMAssay Description:Displacement of [3H]prazosin from Homo sapiens (human) alpha1B adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50403649(CYCLAZOSIN)
Affinity DataKi:  0.309nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328501(CHEMBL1259145 | rac-N-((11-(4-Methylpiperazin-1-yl...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor from human cloneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328480(1-Methyl-4-(8-(1-methyl-1H-pyrazol-5-yl)-10,11-dih...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor from hamster clones.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50403649(CYCLAZOSIN)
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]prazosin from human Alpha-1B adrenoceptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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