Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 1/2'
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoylphenyl)propionic acid | (R)-2-(3-b...)
Affinity DataIC50: 34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50113628([5-(4-Fluoro-phenylcarbamoyl)-pyridin-2-ylsulfanyl...)
Affinity DataIC50: 42nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219799(CHEMBL36535)
Affinity DataIC50: 43nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219797(CHEMBL36934)
Affinity DataIC50: 46nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50088570(2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3-ben...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219796(CHEMBL39464)
Affinity DataIC50: 50nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50475204(CHEMBL192943)
Affinity DataIC50: 80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219800(CHEMBL432475)
Affinity DataIC50: 83nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219806(CHEMBL291140)
Affinity DataIC50: 94nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219809(CHEMBL36643)
Affinity DataIC50: 110nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219811(CHEMBL39710)
Affinity DataIC50: 160nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219812(CHEMBL36842)
Affinity DataIC50: 200nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219794(CHEMBL289656)
Affinity DataIC50: 220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219808(CHEMBL288527)
Affinity DataIC50: 220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214182(CHEMBL438929)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219810(CHEMBL288876)
Affinity DataIC50: 360nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219795(CHEMBL40080)
Affinity DataIC50: 410nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219789(CHEMBL40955)
Affinity DataIC50: 680nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219793(CHEMBL289789)
Affinity DataIC50: 760nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214157(CHEMBL411239)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214158(CHEMBL441586)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219790(CHEMBL39937)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214188(CHEMBL216870)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214188(CHEMBL216870)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219801(CHEMBL40558)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214185(CHEMBL412507)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219798(CHEMBL39988)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214155(CHEMBL413914)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219792(CHEMBL40114)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50213962(CHEMBL410765)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214192(CHEMBL428833)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214193(CHEMBL410889)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50213962(CHEMBL410765)
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was tested for inhibitory activity against Interleukin-8 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219788(CHEMBL36797)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219807(CHEMBL288457)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50113636([5-(4-Fluoro-phenylcarbamoyl)-pyridin-2-ylsulfanyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50219791(CHEMBL35938)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214184(CHEMBL438420)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214173(CHEMBL442313)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214187(CHEMBL415828)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214156(CHEMBL414166)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214190(CHEMBL266910)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214160(CHEMBL436775)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214152(CHEMBL439107)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214178(CHEMBL439291)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50214154(CHEMBL443593)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibitory activity against interleukin-8 receptor using [125I]IL8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

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