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Report error Found 3509 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 4'
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515869(CHEMBL4577408)
Affinity DataKi:  0.220nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515853(CHEMBL4573177)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50547697(CHEMBL4739913)
Affinity DataKi:  0.360nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515868(CHEMBL4521611)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM16668(2,2-dimethyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50331835(5-(2-methyl-propylamido)-2-sulfamoyl-1,3,4-thiadia...)
Affinity DataKi:  0.440nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50230195(CHEMBL4100903)
Affinity DataKi:  0.440nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515873(CHEMBL4586855)
Affinity DataKi:  0.520nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50209283(CHEMBL3885230)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515874(CHEMBL4550339)
Affinity DataKi:  0.590nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50087247(5-{4-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of bovine Carbonic anhydrase IV determined by esterase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515843(CHEMBL4446872)
Affinity DataKi:  0.610nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50209288(CHEMBL3885451)
Affinity DataKi:  0.640nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515878(CHEMBL4569748)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50209225(CHEMBL3883807)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515877(CHEMBL4462700)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50230205(CHEMBL4088636)
Affinity DataKi:  0.730nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50331833(5-propylamido-2-sulfamoyl-1,3,4-thiadiazole | CHEM...)
Affinity DataKi:  0.780nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50230197(CHEMBL4060402)
Affinity DataKi:  0.790nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50080684(5-(4-aminophenylsulfonylimino)-4-methyl-4,5-dihydr...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50084563(5-(4-Amino-benzenesulfonylimino)-4-methyl-4,5-dihy...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50114157((R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50084563(5-(4-Amino-benzenesulfonylimino)-4-methyl-4,5-dihy...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50230196(CHEMBL4096350)
Affinity DataKi:  0.810nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515846(CHEMBL4586708)
Affinity DataKi:  0.890nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589828(CHEMBL5197745)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515848(CHEMBL4476050)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589822(CHEMBL5207894)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589823(CHEMBL5199926)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589824(CHEMBL5177103)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50082759(CHEMBL3423268)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589825(CHEMBL5193273)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50082763(CHEMBL3423262)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589826(CHEMBL5183301)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50589827(CHEMBL5192003)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50209282(CHEMBL3883491)
Affinity DataKi:  0.950nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515866(CHEMBL4593200)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50114120((R)-4-((2R,6S,7S,8S,10R,12S)-10,13-Dimethyl-3,7,12...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50114129(4-((6R,7S,8S,10R,11S,12S,14S,15R)-3,12-Di(R)-hydro...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515865(CHEMBL4440330)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50088778(CHEMBL275565 | N,N-dialkylthio-carbonylsulfenylami...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50114147((R)-4-((5S,6R,8S,9S,12S,14R,17S)-7-Hydroxy-3-(R)-h...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515867(CHEMBL4475435)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50369931(CHEMBL4167555)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human membrane-anchored carbonic anhydrase 4 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to testing by pheno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515559(CHEMBL4435078)
Affinity DataKi:  1.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM11631(2-N-(4-amino-3,5-dibromobenzene)-1,3,4-thiadiazole...)
Affinity DataKi:  1.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50209290(CHEMBL3883755)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50515875(CHEMBL4469501)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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