Report error Found 286 Enz. Inhib. hit(s) with Target = 'Caspase-6'
Affinity DataKi: 120nM ΔG°: -39.5kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 190nM ΔG°: -38.4kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 540nM ΔG°: -35.8kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -34.2kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nM ΔG°: -33.4kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nM ΔG°: -32.2kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -32.1kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 9.70E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+4nM ΔG°: -26.6kJ/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 5.70E+4nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+5nMAssay Description:Inhibition of human caspase 6More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against caspase-6 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory concentration against casp-6 in neuronal precursor (NT2) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of caspase 6 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-6 compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of compound required against Caspase-6 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-6 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Binding affinity of the compound towards human Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 60.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human caspase 6More data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 188nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
Affinity DataIC50: 216nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 241nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
Affinity DataIC50: 305nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 308nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibition of human recombinant caspase 6More data for this Ligand-Target Pair
