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Report error Found 1177 Enz. Inhib. hit(s) with Target = 'Coagulation factor I...
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241371(US9409908, 3 | US9951071, Example 3)
Affinity DataKi:  0.0300nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241399(US9409908, 31 | US9951071, Example 31)
Affinity DataKi:  0.0400nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241567(US9409908, 199 | US9951071, Example 199)
Affinity DataKi: <0.0500nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241566(US9409908, 198 | US9951071, Example 198)
Affinity DataKi: <0.0500nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241552(US9409908, 184 | US9951071, Example 184)
Affinity DataKi: <0.0500nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241436(US9409908, 68 | US9951071, Example 68)
Affinity DataKi:  0.0500nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241503(US9409908, 135 | US9951071, Example 135)
Affinity DataKi:  0.0500nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241451(US9409908, 83 | US9951071, Example 83)
Affinity DataKi:  0.0600nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241400(US9409908, 32 | US9951071, Example 32)
Affinity DataKi:  0.0600nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241583(US9409908, 215 | US9951071, Example 215)
Affinity DataKi:  0.0700nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241421(US9409908, 53 | US9951071, Example 53)
Affinity DataKi:  0.0800nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241422(US9409908, 54 | US9951071, Example 54)
Affinity DataKi:  0.0800nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241404(US9409908, 36 | US9951071, Example 36)
Affinity DataKi:  0.0900nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241394(US9409908, 26 | US9951071, Example 26)
Affinity DataKi:  0.0900nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241468(US9409908, 100 | US9951071, Example 100)
Affinity DataKi:  0.0900nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241472(US9409908, 104 | US9951071, Example 104)
Affinity DataKi:  0.0900nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241549(US9409908, 181 | US9951071, Example 181)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241393(US9409908, 25 | US9951071, Example 25)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241550(US9409908, 182 | US9951071, Example 182)
Affinity DataKi:  0.110nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241412(US9409908, 44 | US9951071, Example 44)
Affinity DataKi:  0.130nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241470(US9409908, 102 | US9951071, Example 102)
Affinity DataKi:  0.150nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241539(US9409908, 171 | US9951071, Example 171)
Affinity DataKi:  0.170nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241548(US9409908, 180)
Affinity DataKi:  0.180nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241528(US9409908, 160 | US9951071, Example 160)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241398(US9409908, 30 | US9951071, Example 30)
Affinity DataKi:  0.210nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241370(US9409908, 2 | US9951071, Example 2)
Affinity DataKi:  0.230nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241559(US9409908, 191 | US9951071, Example 191)
Affinity DataKi:  0.230nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241558(US9409908, 190 | US9951071, Example 190)
Affinity DataKi:  0.270nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241449(US9409908, 81 | US9951071, Example 81)
Affinity DataKi:  0.310nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241411(US9409908, 43 | US9951071, Example 43)
Affinity DataKi:  0.380nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241541(US9409908, 173 | US9951071, Example 173)
Affinity DataKi:  0.420nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241555(US9409908, 187 | US9951071, Example 187)
Affinity DataKi:  0.440nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241410(US9409908, 42 | US9951071, Example 42)
Affinity DataKi:  0.450nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241389(US9409908, 21 | US9951071, Example 21)
Affinity DataKi:  0.460nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241563(US9409908, 195 | US9951071, Example 195)
Affinity DataKi:  0.470nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241447(US9409908, 79 | US9951071, Example 79)
Affinity DataKi:  0.550nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241460(US9409908, 92 | US9951071, Example 92)
Affinity DataKi:  0.560nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241459(US9409908, 91 | US9951071, Example 91)
Affinity DataKi:  0.560nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241529(US9409908, 161 | US9951071, Example 161)
Affinity DataKi:  0.590nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50126919(CHEMBL3629114)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50126916(CHEMBL3629111 | US10351558, Example 139)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241478(US9409908, 110 | US9951071, Example 110)
Affinity DataKi:  0.620nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241407(US9409908, 39 | US9951071, Example 39)
Affinity DataKi:  0.670nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241409(US9409908, 41 | US9951071, Example 41)
Affinity DataKi:  0.690nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241454(US9409908, 86 | US9951071, Example 86)
Affinity DataKi:  0.720nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241564(US9409908, 196 | US9951071, Example 196)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50126872(CHEMBL3628964)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241441(US9409908, 177 | US9409908, 178 | US9409908, 73 | ...)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241535(US9409908, 167 | US9951071, Example 167)
Affinity DataKi:  0.810nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241519(US9409908, 151 | US9951071, Example 151)
Affinity DataKi:  0.840nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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