Compile Data Set for Download or QSAR
Report error Found 25212 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor'
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50007522(CHEMBL289330 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataKi:  0.00300nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50008782(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM84928(CAS_125368 | NSC_125368 | FK 1052)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Mouse)
Medical Research Service

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50005120(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50090828((-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-...)
Affinity DataEC50:  0.0130nMAssay Description:Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0140nMAssay Description:Binding affinity to Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr by beta scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601573(CHEMBL5208845)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601568(CHEMBL5178472)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601576(CHEMBL5184911)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601574(CHEMBL5201074)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601579(CHEMBL5202592)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601577(CHEMBL5180504)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601589(CHEMBL5176229)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601583(CHEMBL5198795)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601552(CHEMBL5183205)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601563(CHEMBL5204599)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601556(CHEMBL5200771)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601568(CHEMBL5178472)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601556(CHEMBL5200771)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601552(CHEMBL5183205)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601563(CHEMBL5204599)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601574(CHEMBL5201074)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601573(CHEMBL5208845)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601577(CHEMBL5180504)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601576(CHEMBL5184911)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601583(CHEMBL5198795)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601579(CHEMBL5202592)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50601589(CHEMBL5176229)
Affinity DataKd:  0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.0150nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0160nMAssay Description:Binding affinity to Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cells after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50368742(CHEMBL1169525)
Affinity DataKi:  0.0170nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50007522(CHEMBL289330 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataKi:  0.0180nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50040079(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo...)
Affinity DataKi:  0.0190nMAssay Description:Compound was evaluated for the inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060602(2-[3-((2R,8aS)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]p...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p (Pre treated with 1 nM) calculated for the high affinity components of the [3H]spiroperidol b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50005120(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50042730(4-Amino-5-chloro-N-[5-(4-fluoro-benzyl)-octahydro-...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50220541(N-(((S)-1-allylpyrrolidin-2-yl)methyl)-5-(3-fluoro...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50008785(CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...)
Affinity DataKi:  0.0200nMAssay Description:Compound was evaluated for the inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institutet

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Fujisawa Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50368060(CHEMBL1907695)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
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